VDR signaling inhibits cancer-associated-fibroblasts' release of exosomal miR-10a-5p and limits their supportive effects on pancreatic cancer cells

Gut. 2019 May;68(5):950-951. doi: 10.1136/gutjnl-2018-316627. Epub 2018 Apr 25.

Authors

Fanyang Kong^#¹, Lei Li^#¹, Guokun Wang^#², Xuan Deng³, Zhaoshen Li¹, Xiangyu Kong¹

Affiliations

¹ Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China.
² Key Laboratory of Digestive Disease, Yinzhou Hospital, Medical School of Ningbo University, Ningbo, Zhejiang, China.
³ Department of Laboratory Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

^# Contributed equally.

PMID: 29695492
DOI: 10.1136/gutjnl-2018-316627

No abstract available

Keywords: pancreatic cancer; vitamin D receptor gene.

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Cancer-Associated Fibroblasts*
Colorectal Neoplasms*
Humans
MicroRNAs*
Pancreatic Neoplasms*
Receptors, Calcitriol

Substances

MicroRNAs
Receptors, Calcitriol
VDR protein, human