Complete response to CSF1R inhibitor in a translocation variant of teno-synovial giant cell tumor without genomic alteration of the CSF1 gene

Ann Oncol. 2018 Jun 1;29(6):1488-1489. doi: 10.1093/annonc/mdy129.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminopyridines / therapeutic use*
  • Female
  • Giant Cell Tumors / drug therapy*
  • Giant Cell Tumors / genetics
  • Giant Cell Tumors / pathology
  • Humans
  • Macrophage Colony-Stimulating Factor / genetics*
  • Middle Aged
  • Prognosis
  • Pyrroles / therapeutic use*
  • Receptors, Granulocyte-Macrophage Colony-Stimulating Factor / antagonists & inhibitors*
  • Receptors, Granulocyte-Macrophage Colony-Stimulating Factor / genetics
  • Remission Induction
  • Synovial Membrane / drug effects*
  • Synovial Membrane / metabolism
  • Synovial Membrane / pathology
  • Translocation, Genetic*

Substances

  • Aminopyridines
  • CSF1 protein, human
  • CSF1R protein, human
  • Pyrroles
  • Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
  • pexidartinib
  • Macrophage Colony-Stimulating Factor