Oxidative Radical Intermolecular Trifluoromethylthioarylation of Styrenes by Arenediazonium Salts and Copper(I) Trifluoromethylthiolate

J Org Chem. 2018 May 18;83(10):5836-5843. doi: 10.1021/acs.joc.8b00650. Epub 2018 Apr 20.

Abstract

An efficient oxidative radical intermolecular trifluoromethylthioarylation of styrenes with arenediazonium salts and copper(I) trifluoromethylthiolate under mild conditions is described for the first time. The reactions provide good yields of the corresponding trifluoromethylthioarylation products with broad substrate scope and excellent functional group compatibility.

Publication types

  • Research Support, Non-U.S. Gov't