Response to comment on " Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis"

Sci Transl Med. 2018 Mar 21;10(433):eaao3031. doi: 10.1126/scitranslmed.aao3031.

¹ Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
² Division of Rheumatology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA.
³ Department of Periodontology, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
⁴ Department of Applied Oral Sciences, Forsyth Institute, Cambridge, MA 02142, USA.
⁵ National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.
⁶ Division of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA. andrade@jhmi.edu.

Abstract

Antibodies to leukotoxin A are markers that link Aggregatibacter actinomycetemcomitans-associated periodontitis and rheumatoid arthritis.