Central nervous system lesions in scrub typhus rediscovered: An autopsy report

Neurol India. 2018 Mar-Apr;66(2):434-438. doi: 10.4103/0028-3886.227309.

Abstract

While neurological manifestations in scrub typhus have been well described both in clinical and radiological reports in the literature, neuropathological features are rarely reported. They range from subtle "typhus nodules" to more widespread capillaritis. Familiarity with pathological features is essential for correct interpretation. We describe the clinical, imaging, and histological findings in an autopsy case of scrub typhus, which was pre-terminally superimposed by fungal meningoencephalitis. Interestingly, the autopsy revealed morphological evidence of both etiologies.

Keywords: Autopsy; central nervous system infections; pathology; scrub typhus.

Publication types

  • Case Reports

MeSH terms

  • Autopsy / methods
  • Brain / metabolism
  • Brain / pathology*
  • Central Nervous System Diseases / diagnostic imaging
  • Central Nervous System Diseases / etiology*
  • Central Nervous System Diseases / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Scrub Typhus / complications*
  • Scrub Typhus / diagnostic imaging