Contributions of BMPR2 Mutations and Extrinsic Factors to Cellular Phenotypes of Pulmonary Arterial Hypertension Revealed by Induced Pluripotent Stem Cell Modeling

Am J Respir Crit Care Med. 2018 Jul 15;198(2):271-275. doi: 10.1164/rccm.201801-0049LE.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bone Morphogenetic Protein Receptors, Type II / genetics*
  • Familial Primary Pulmonary Hypertension / genetics*
  • Familial Primary Pulmonary Hypertension / physiopathology*
  • Female
  • Humans
  • Induced Pluripotent Stem Cells*
  • Male
  • Middle Aged
  • Mutation*
  • Phenotype*

Substances

  • Bone Morphogenetic Protein Receptors, Type II