Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Haematologica. 2018 Aug;103(8):e368-e371. doi: 10.3324/haematol.2017.186601. Epub 2018 Mar 15.

¹ Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
² Department of Exploratory Toxicology, Celgene, San Diego, CA, USA.
³ Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, the Netherlands.
⁴ Department of Hematology, Maastricht University Medical Center, the Netherlands.
⁵ Department of Hematology, Erasmus Medical Center, Rotterdam, the Netherlands.
⁶ Department of Internal Medicine, Meander Medical Center, Amersfoort, the Netherlands.
⁷ Department of Hematology, St. Antonius Hospital, Nieuwegein, the Netherlands.
⁸ Laboratory for Translational Immunology, University Medical Center Utrecht, the Netherlands.
⁹ Department of Internal Medicine, Spaarne Hospital, Hoofddorp, the Netherlands.
¹⁰ Department of Internal Medicine, Rode Kruis Hospital, Beverwijk, the Netherlands.
¹¹ Department of Internal Medicine, Rijnstate Hospital, Arnhem, the Netherlands.
¹² Department of Hematology, University Medical Center Utrecht Cancer Center, the Netherlands.
¹³ Department of Pathology, University Medical Center Utrecht, the Netherlands.
¹⁴ Department of Translational Development, Celgene Corporation, Summit, NJ, USA.
¹⁵ Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands n.vandedonk@vumc.nl.

No abstract available

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