Clonality and clonal evolution analysis of paediatric ALL based on B-cell receptor/T-cell receptor rearrangement

Br J Haematol. 2019 Mar;184(5):829-833. doi: 10.1111/bjh.15179. Epub 2018 Mar 13.

Authors

Ling-Wen Ding¹, Kar-Tong Tan¹, Qiao-Yang Sun¹, Zhen-Tang Lao^{1

2}, Henry Yang¹, Nan Jiang³, Wenwen Chien⁴, Jin-Fen Xiao¹, Xin-Yi Loh¹, Mo-Li Huang¹, Michael Lill⁴, De-Chen Lin⁴, Allen Eng Juh Yeoh^{1

3}, H Phillip Koeffler^{1

4}

Affiliations

¹ Cancer Science Institute of Singapore, National University of Singapore, Singapore.
² Department of Haematology, Singapore General Hospital, Singapore.
³ Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
⁴ Division of Hematology/Oncology, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, USA.

PMID: 29532914
DOI: 10.1111/bjh.15179

No abstract available

Keywords: BCR/T-cell receptor repertoire; clonal evolution; paediatric ALL; relapse.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Child
Clonal Evolution*
Humans
Neoplasm Proteins / genetics*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
Receptors, Antigen, B-Cell / genetics*
Receptors, Antigen, T-Cell / genetics*

Substances

Neoplasm Proteins
Receptors, Antigen, B-Cell
Receptors, Antigen, T-Cell