Abstract
Studies of the effects of Trichoderma harzianum Rifai F-180 culture fluid concentrate containing L-lysine-α-oxidase antitumor enzyme produced by the fungus and the homogenous enzyme, on ultrahazardous bacterium Acidovorax citrulli demonstrated the antibacterial activity of the concentrate. Trichoderma harzianum Rifai F-180 producing L-lysine-α-oxidase was cultured in a technological device at G. K. Skryabin Institute of Biochemistry and. Physiology of Microorganisms, Russian Academy of Sciences. Activity of L-lysine-α-oxidase in the resulted culture fluid concentrate was 0.54 U/ml, activity of the homogenous enzyme was 50 U/mg.
Keywords:
Acidovorax citrulli; L-lysine-α-oxidase antitumor enzyme; Trichoderma culture fluid.
MeSH terms
-
Amino Acid Oxidoreductases / isolation & purification
-
Amino Acid Oxidoreductases / pharmacology*
-
Antineoplastic Agents / isolation & purification
-
Antineoplastic Agents / pharmacology
-
Comamonadaceae / drug effects*
-
Comamonadaceae / growth & development
-
Comamonadaceae / isolation & purification
-
Comamonadaceae / pathogenicity
-
Disk Diffusion Antimicrobial Tests
-
Drug Repositioning
-
Fungal Proteins / isolation & purification
-
Fungal Proteins / pharmacology*
-
Fungicides, Industrial / isolation & purification
-
Fungicides, Industrial / pharmacology*
-
Plants / microbiology
-
Trichoderma / chemistry*
-
Trichoderma / growth & development
Substances
-
Antineoplastic Agents
-
Fungal Proteins
-
Fungicides, Industrial
-
Amino Acid Oxidoreductases
-
L-lysine oxidase