Detection and genetic characterization of porcine pegivirus in pigs in the United States

C Yang; L Wang; H Shen; Y Zheng; S A Bade; P C Gauger; Q Chen; J Zhang; B Guo; K-J Yoon; K M Harmon; R G Main; G Li

doi:10.1111/tbed.12844

Detection and genetic characterization of porcine pegivirus in pigs in the United States

Transbound Emerg Dis. 2018 Jun;65(3):618-626. doi: 10.1111/tbed.12844. Epub 2018 Feb 27.

Authors

C Yang^{1

2}, L Wang³, H Shen¹, Y Zheng¹, S A Bade¹, P C Gauger¹, Q Chen¹, J Zhang¹, B Guo¹, K-J Yoon¹, K M Harmon¹, R G Main¹, G Li¹

Affiliations

¹ Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA.
² China Institute of Veterinary Drug Control, Beijing, China.
³ Department of Veterinary Clinical Medicine and the Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Illinois, Urbana, IL, USA.

PMID: 29484834
DOI: 10.1111/tbed.12844

Abstract

Using next-generation sequencing on vesicular swab and serum from swine from the USA exhibiting lameness and vesicles, porcine pegivirus (PPgV) was first identified and genetically characterized in the United States. Further screening using RT-PCR revealed that 24 of 159 (15.1%) serum samples were positive for PPgV. Future studies are needed to understand clinical impacts of the virus.

Keywords: United States; characterization; complete genome; detection; porcine pegivirus.

MeSH terms

Animals
Flaviviridae / genetics*
Flaviviridae / isolation & purification*
Flavivirus Infections / genetics*
High-Throughput Nucleotide Sequencing*
Phylogeny
Swine
Swine Diseases / virology*
United States

Associated data

GENBANK/MG595745
GENBANK/MG595746
GENBANK/MG595747