Comparison of two prognostic models in trauma outcome

Br J Surg. 2018 Apr;105(5):513-519. doi: 10.1002/bjs.10764. Epub 2018 Feb 21.

Abstract

Background: The Trauma Audit and Research Network (TARN) in the UK publicly reports hospital performance in the management of trauma. The TARN risk adjustment model uses a fractional polynomial transformation of the Injury Severity Score (ISS) as the measure of anatomical injury severity. The Trauma Mortality Prediction Model (TMPM) is an alternative to ISS; this study compared the anatomical injury components of the TARN model with the TMPM.

Methods: Data from the National Trauma Data Bank for 2011-2015 were analysed. Probability of death was estimated for the TARN fractional polynomial transformation of ISS and compared with the TMPM. The coefficients for each model were estimated using 80 per cent of the data set, selected randomly. The remaining 20 per cent of the data were used for model validation. TMPM and TARN were compared using calibration curves, measures of discrimination (area under receiver operating characteristic curves; AUROC), proximity to the true model (Akaike information criterion; AIC) and goodness of model fit (Hosmer-Lemeshow test).

Results: Some 438 058 patient records were analysed. TMPM demonstrated preferable AUROC (0·882 for TMPM versus 0·845 for TARN), AIC (18 204 versus 21 163) and better fit to the data (32·4 versus 153·0) compared with TARN.

Conclusion: TMPM had greater discrimination, proximity to the true model and goodness-of-fit than the anatomical injury component of TARN. TMPM should be considered for the injury severity measure for the comparative assessment of trauma centres.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Databases, Factual
  • Female
  • Humans
  • Male
  • Middle Aged
  • Models, Statistical*
  • Prognosis
  • ROC Curve
  • Retrospective Studies
  • Risk Assessment / statistics & numerical data*
  • Survival Rate / trends
  • Trauma Centers / statistics & numerical data*
  • Trauma Severity Indices
  • United Kingdom / epidemiology*
  • Wounds and Injuries / diagnosis*
  • Wounds and Injuries / mortality