A case and literature review of orbital microcystic adnexal carcinoma

Orbit. 2018 Dec;37(6):472-475. doi: 10.1080/01676830.2018.1440607. Epub 2018 Feb 20.

Abstract

Microcystic adnexal carcinoma (MAC) is a very rare and locally aggressive sweat gland tumour. MAC has been well reported presenting as a periocular cutaneous lesion, rarely with subsequent direct orbital invasion and only once as a primary orbital lesion. Local recurrence is frequent after primary surgical excision and the role of adjuvant radiotherapy is ill-defined. We describe a case of orbital MAC treated successfully with radiotherapy after incomplete margin clearance post exenteration surgery and review the associated literature.

Keywords: Microcystic adnexal carcinoma; exenteration; radiotherapy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Combined Modality Therapy
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Ophthalmologic Surgical Procedures
  • Orbital Neoplasms / diagnostic imaging
  • Orbital Neoplasms / pathology*
  • Orbital Neoplasms / therapy
  • Radiotherapy
  • Sweat Gland Neoplasms / diagnostic imaging
  • Sweat Gland Neoplasms / pathology*
  • Sweat Gland Neoplasms / therapy
  • Tomography, X-Ray Computed