Deep coma does not always predict poor outcomes among patients with polytrauma

Eur J Trauma Emerg Surg. 2019 Jun;45(3):455-460. doi: 10.1007/s00068-018-0917-8. Epub 2018 Feb 9.

Abstract

Purposes: This study aimed to clarify the prognosis of polytrauma patients presenting to the emergency department (ED) with a Glasgow Coma Scale score (GCS) of 3.

Methods: A trauma registry system has been established at our institution since 2009. The current study reviewed patients in the registry who presented to the ED with a GCS of 3 from January 2011 to December 2015. Surviving and non-surviving patients were compared to identify the prognostic factors of patient survival. The study also aimed to determine the factors contributing to patients who survived with a GCS > 13 at discharge.

Results: During the study period, 145 patients were enrolled in the study, 119 of whom (82.1%) did not survive the traumatic insult. Of the 26 survivors, 13 (9.0%) had a GCS of 14 or 15 at discharge. The multiple logistic regression revealed that a lack of bilateral dilated and fixed pupils (BFDP) (OR 5.967, 95% CI 1.780-19.997, p = 0.004) and a GCS > 3 after resuscitation (OR 6.875, 95% CI 2.135-22.138, p = 0.001) were independent prognostic factors of survival. Based on the multiple logistic regression, an age under 40 years (OR 16.405, 95% CI 1.520-177.066, p = 0.021) and a GCS > 3 after resuscitation (OR 12.100, 95% CI 1.058-138.352, p = 0.045) were independent prognostic factors of a GCS > 13 at discharge.

Conclusion: Aggressive resuscitation still provided benefit to polytrauma patients presenting with a GCS of 3, especially those with a rapid response to the resuscitation. Young patients with a deep coma on arrival had a higher probability of functional recovery after resuscitation in the ED.

Keywords: Coma; Glasgow Coma Scale; Mortality; Multiple trauma; Recovery of function; Traumatic brain injuries.

MeSH terms

  • Abbreviated Injury Scale
  • Abdominal Injuries / epidemiology
  • Abdominal Injuries / therapy
  • Adult
  • Age Factors
  • Aged
  • Coma, Post-Head Injury / epidemiology
  • Coma, Post-Head Injury / physiopathology*
  • Craniocerebral Trauma / epidemiology
  • Craniocerebral Trauma / physiopathology
  • Craniocerebral Trauma / therapy
  • Extremities / injuries
  • Female
  • Glasgow Coma Scale
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Mortality
  • Multiple Trauma / epidemiology
  • Multiple Trauma / physiopathology*
  • Multiple Trauma / therapy
  • Prognosis
  • Pupil Disorders / epidemiology*
  • Recovery of Function
  • Reflex, Pupillary
  • Resuscitation
  • Retrospective Studies
  • Taiwan / epidemiology
  • Thoracic Injuries / epidemiology
  • Thoracic Injuries / therapy