Abstract
A novel immune-modulatory therapy utilizing targeted delivery of cytokines to draining lymph nodes effectively reprograms Th2 allergic responses towards a Th1 and tolerogenic profile, resulting in protection from peanut antigen-induced anaphylaxis.
Publication types
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Letter
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Research Support, N.I.H., Extramural
MeSH terms
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Allergens / immunology*
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Animals
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Female
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Food / adverse effects*
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Food Hypersensitivity / immunology*
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Humans
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Immunity / immunology*
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Immunotherapy / methods
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Mice
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Mice, Inbred C57BL
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Th1 Cells / immunology
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Th2 Cells / immunology