Blastic plasmacytoid dendritic cell neoplasm with unusual morphology, MYC rearrangement and TET2 and DNMT3A mutations

Br J Haematol. 2018 May;181(3):305. doi: 10.1111/bjh.15128. Epub 2018 Feb 7.

Authors

Habibe Kurt¹, Joseph D Khoury¹, L Jeffrey Medeiros¹, Yang O Huh¹

Affiliation

¹ Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

PMID: 29411884
DOI: 10.1111/bjh.15128

No abstract available

Publication types

Case Reports

MeSH terms

Aged
Blast Crisis* / genetics
Blast Crisis* / metabolism
DNA (Cytosine-5-)-Methyltransferases* / genetics
DNA (Cytosine-5-)-Methyltransferases* / metabolism
DNA Methyltransferase 3A
DNA-Binding Proteins* / genetics
DNA-Binding Proteins* / metabolism
Dendritic Cells* / metabolism
Dendritic Cells* / pathology
Dioxygenases
Humans
Leukemia, Myeloid, Acute* / genetics
Leukemia, Myeloid, Acute* / metabolism
Leukemia, Myeloid, Acute* / pathology
Male
Mutation*
Plasma Cells* / metabolism
Plasma Cells* / pathology
Proto-Oncogene Proteins c-myc* / genetics
Proto-Oncogene Proteins c-myc* / metabolism
Proto-Oncogene Proteins* / genetics
Proto-Oncogene Proteins* / metabolism

Substances

DNA-Binding Proteins
DNMT3A protein, human
MYC protein, human
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-myc
Dioxygenases
TET2 protein, human
DNA (Cytosine-5-)-Methyltransferases
DNA Methyltransferase 3A