Polymorphism rs2476601 in the PTPN22 gene is associated with type 1 diabetes in children from the South Region of Brazil

Gene. 2018 Apr 15:650:15-18. doi: 10.1016/j.gene.2018.01.073. Epub 2018 Feb 2.

Authors

Marciane Welter¹, Waldemar Volanski¹, Dayane Alberton¹, Suzana Nesi França², Geraldo Picheth¹, Fabiane Gomes de Moraes Rego³

Affiliations

¹ Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Paraná, Brazil.
² Pediatric Endocrinology Unit, Department of Pediatrics, Federal University of Paraná, Curitiba, Paraná, Brazil.
³ Postgraduate Program in Pharmaceutical Sciences, Federal University of Paraná, Curitiba, Paraná, Brazil. Electronic address: rego@ufpr.br.

PMID: 29408732
DOI: 10.1016/j.gene.2018.01.073

No abstract available

Keywords: Case-control study; Genetic variability; PTPN22; SNPs; Type 1 diabetes mellitus.

Publication types

Letter

MeSH terms

Adolescent
Alleles
Brazil
Case-Control Studies
Child
Diabetes Mellitus, Type 1 / genetics*
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Genetic Variation
Humans
Male
Polymorphism, Single Nucleotide / genetics
Protein Tyrosine Phosphatase, Non-Receptor Type 22 / genetics*
Protein Tyrosine Phosphatase, Non-Receptor Type 22 / metabolism
Risk Factors

Substances

PTPN22 protein, human
Protein Tyrosine Phosphatase, Non-Receptor Type 22