[A Case of Granulocyte-Colony Stimulating Factor Producing Breast Cancer That Caused Rapid Progression]

Gan To Kagaku Ryoho. 2017 Nov;44(12):1257-1259.
[Article in Japanese]

Abstract

We report a case of granulocyte-colony stimulating factor(G-CSF)producing breast cancer in a 54-year-old woman. Eight months after surgery, multiple liver and pulmonary metastases appeared. They progressed rapidly in 2 weeks and she had a high fever of 38 degrees. Serum G-CSF was high, and positive cells were found by immunostaining of the primary tumor. Chemotherapy was initially successful but she died 4 months after relapse.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Breast Neoplasms / chemistry
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / pathology
  • Breast Neoplasms / therapy*
  • Combined Modality Therapy
  • Disease Progression
  • Fatal Outcome
  • Female
  • Granulocyte Colony-Stimulating Factor / biosynthesis*
  • Granulocyte Colony-Stimulating Factor / blood
  • Humans
  • Liver Neoplasms / secondary
  • Liver Neoplasms / therapy
  • Lung Neoplasms / secondary
  • Lung Neoplasms / therapy
  • Middle Aged
  • Recurrence
  • Time Factors

Substances

  • Granulocyte Colony-Stimulating Factor