Repurposing Metformin for Cardiovascular Disease

Circulation. 2018 Jan 30;137(5):422-424. doi: 10.1161/CIRCULATIONAHA.117.031735.
No abstract available

Keywords: cardiovascular diseases; diabetes mellitus, type 2; metabolic syndrome; metformin; randomized controlled trial.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Inflammatory Agents / adverse effects
  • Anti-Inflammatory Agents / therapeutic use*
  • Cardiovascular Agents / adverse effects
  • Cardiovascular Agents / therapeutic use*
  • Cardiovascular Diseases / drug therapy*
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / metabolism
  • Cardiovascular Diseases / physiopathology
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetes Mellitus, Type 2 / epidemiology
  • Drug Repositioning*
  • Humans
  • Hypoglycemic Agents / adverse effects
  • Hypoglycemic Agents / therapeutic use*
  • Inflammation Mediators / antagonists & inhibitors
  • Inflammation Mediators / metabolism
  • Metformin / adverse effects
  • Metformin / therapeutic use*
  • Randomized Controlled Trials as Topic
  • Signal Transduction / drug effects

Substances

  • Anti-Inflammatory Agents
  • Cardiovascular Agents
  • Hypoglycemic Agents
  • Inflammation Mediators
  • Metformin