Nigrosporanenes C and D, two new cyclohexene derivatives from the enphytic fungus Nigrospora oryzae S4

J Asian Nat Prod Res. 2018 Oct;20(10):957-961. doi: 10.1080/10286020.2018.1424140. Epub 2018 Jan 15.

Abstract

Two new cyclohexene derivatives, nigrosporanenes C and D (1 and 2), together with three known compounds (3-5), were isolated from the culture of an endophyte Nigrospora oryzae S4. Their structures were characterized by a combination of detailed spectroscopic analysis and comparison of their NMR data with those reported in the literature. All compounds were tested for anti-phytopathogenic activity, however, none of them showed activity at a concentration of 20 μM.

Keywords: S4; Endophyte; nigrosporanene.

MeSH terms

  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / pharmacology*
  • Ascomycota / chemistry*
  • Ascomycota / metabolism
  • Cyclohexenes / chemistry
  • Cyclohexenes / isolation & purification*
  • Cyclohexenes / pharmacology
  • Endophytes / chemistry*
  • Endophytes / metabolism
  • Magnetic Resonance Spectroscopy

Substances

  • Antifungal Agents
  • Cyclohexenes