Dabrafenib and trametinib combination therapy safely performed in a patient with metastatic melanoma after severe liver toxicity due to vemurafenib

J Dermatol. 2018 Jun;45(6):e157-e158. doi: 10.1111/1346-8138.14206. Epub 2018 Jan 6.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Chemical and Drug Induced Liver Injury / diagnosis
  • Chemical and Drug Induced Liver Injury / etiology*
  • Female
  • Humans
  • Imidazoles / therapeutic use
  • Liver Function Tests
  • Melanoma / drug therapy*
  • Oximes / therapeutic use
  • Pyridones / therapeutic use
  • Pyrimidinones / therapeutic use
  • Severity of Illness Index
  • Skin Neoplasms / drug therapy*
  • Vemurafenib / adverse effects*

Substances

  • Imidazoles
  • Oximes
  • Pyridones
  • Pyrimidinones
  • Vemurafenib
  • trametinib
  • dabrafenib