[Risk and related factors on metabolic syndrome among people who had received screening on physical check-up programs, in China]

Abstract

Objective: To explore the risk of developing metabolic syndrome (MS) by using the data from cohorts involving people having received screening programs for physical check-up, in three areas of China (Beijing, Hongkong and Taiwan). Methods: A total number of 6 828 nonmetabolic syndromic adults, who received physical examination for the first time and with records kept for longer than 5 years (between 2004 and 2010) at the MJ centers, were recruited. Criteria developed by the Joint Committee for Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Chinese Adults in 2007 (JCDCG-2007) was used for defining the metabolic syndrome. Cox proportional hazards regression model was used to examine the difference of the risk of developing MS among the three cohorts that received the health screening programs. Results: The standardized incidence densities of MS were 3.14 per 100 person-years, 2.19 per 100 person-years and 2.03 per 100 person-years in the cohorts of Beijing, Hongkong and Taiwan, respectively. After adjusting for gender, age, cigarette smoking, dietary patterns at the baseline, the HRs for people in Beijing and Hongkong were 1.60 (95%CI: 1.34-1.91) and 1.08 (95%CI: 0.83-1.41) respectively, in developing MS, when compared with people from Taiwan. Factors as being male, elderly, cigarette smoking, meat/food intake dietary pattern and MS components at the baseline all showed significantly positive effects on the risk of developing MS. Conclusions: There were significant differences regarding the risk of developing MS among health screening people from the Beijing, Hongkong and Taiwan. Factors as being male, elderly, cigarette smoking, meat/food intake, dietary pattern and MS components at the baseline appear to be the risk factors for developing the MS.

Keywords: Metabolic Syndrome; Regional Differences; Risk Factors.