Understanding Disease Variants through the Lens of Protein Interactions

Jonathan Woodsmith; Ulrich Stelzl

doi:10.1016/j.cels.2017.12.009

Understanding Disease Variants through the Lens of Protein Interactions

Cell Syst. 2017 Dec 27;5(6):544-546. doi: 10.1016/j.cels.2017.12.009.

Authors

Jonathan Woodsmith¹, Ulrich Stelzl²

Affiliations

¹ Institute of Pharmaceutical Sciences, University of Graz and BioTechMed-Graz, Graz, Austria. Electronic address: jonathan.woodsmith@uni-graz.at.
² Institute of Pharmaceutical Sciences, University of Graz and BioTechMed-Graz, Graz, Austria. Electronic address: ulrich.stelzl@uni-graz.at.

PMID: 29284128
DOI: 10.1016/j.cels.2017.12.009

Abstract

High-density interaction mapping of mitochondrial proteins provides clues to molecular mechanisms implicated in the progression of neurological disorders.

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MeSH terms

Homeostasis
Humans
Mitochondria*
Mitochondrial Proteins
NF-kappa B*
Oxidation-Reduction

Substances

Mitochondrial Proteins
NF-kappa B