Signet-ring Cell Carcinoma Derived from a Main Duct-type Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Case Report with Long-term Follow-up

Intern Med. 2018 Apr 15;57(8):1093-1099. doi: 10.2169/internalmedicine.9743-17. Epub 2017 Dec 21.

Abstract

We herein report the case of a 74-year-old man who underwent surgery 9 years after his initial visit and who was pathologically diagnosed with signet-ring cell carcinoma (SRCC) derived from a main-duct-type intraductal papillary mucinous neoplasm (MD-IPMN). At the first imaging examination, only a small pancreatic cyst with mild dilation of the main pancreatic duct (MPD) was detected in the pancreatic head. Eventually, MD-IPMN with mural nodules and MPD dilation (30 mm) developed in the pancreatic body, while the pancreatic head cyst remained unchanged. Total pancreatectomy was performed and the MD-IPMN was pathologically diagnosed as SRCC derived from an intestinal-type MD-IPMN.

Keywords: IPMN; intestinal type; mass forming pancreatitis; signet-ring cell carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Pancreatic Ductal / pathology*
  • Carcinoma, Pancreatic Ductal / surgery
  • Carcinoma, Signet Ring Cell / pathology*
  • Follow-Up Studies
  • Humans
  • Male
  • Pancreatectomy / methods
  • Pancreatic Cyst / pathology
  • Pancreatic Ducts / pathology
  • Pancreatic Neoplasms / diagnosis
  • Pancreatic Neoplasms / pathology*
  • Pancreatic Neoplasms / surgery