Mother-to-child transmission of hepatitis B virus (HBV) is one of major public health issues. Difference is found on effect of preventions of mother to child transmission of HBV such as Hepatitis B vaccine, Hepatitis B immunoglobulin and antiretroviral drugs. Based on the risks of hepatitis B virus on children, influencing factors and interventions of HBV mother-to-child transmission were explored to improve prevention mother-to-child transmission of hepatitis B and to search appropriate strategies reducing mother-to-child transmission of HBV.
HBV母婴传播已成为引起社会关注的重大公共卫生问题之一。目前，乙型肝炎疫苗、乙型肝炎免疫球蛋白和抗病毒药物等不同干预措施预防HBV母婴传播的效果存在差异。本文从儿童感染HBV的途径与危害、影响HBV母婴传播的因素以及HBV传播干预措施等3个方面进行综述，探讨不同因素和干预措施对HBV母婴传播的影响，为提高预防HBV母婴传播的效果，探讨进一步降低HBV母婴传播干预措施的研究方向。.
Keywords: Antiviral agents; Hepatitis B virus; Infectious disease transmission, vertical; Interventions.