Extracellular Vesicles as Biomarkers for the Detection of a Tumor Marker Gene in Epidermolysis Bullosa-Associated Squamous Cell Carcinoma

Yuchen Sun; Katharina Woess; Melanie Kienzl; Victoria M Leb-Reichl; Andrea Feinle; Monika Wimmer; Roland Zauner; Verena Wally; Ursula Luetz-Meindl; Jemima E Mellerio; Ignacia Fuentes; Andrew P South; Johann W Bauer; Julia Reichelt; Tomomi Furihata; Christina Guttmann-Gruber; Josefina Piñón Hofbauer

doi:10.1016/j.jid.2017.11.022

Extracellular Vesicles as Biomarkers for the Detection of a Tumor Marker Gene in Epidermolysis Bullosa-Associated Squamous Cell Carcinoma

J Invest Dermatol. 2018 May;138(5):1197-1200. doi: 10.1016/j.jid.2017.11.022. Epub 2017 Dec 2.

Authors

Yuchen Sun¹, Katharina Woess², Melanie Kienzl², Victoria M Leb-Reichl², Andrea Feinle³, Monika Wimmer², Roland Zauner², Verena Wally², Ursula Luetz-Meindl⁴, Jemima E Mellerio⁵, Ignacia Fuentes⁶, Andrew P South⁷, Johann W Bauer⁸, Julia Reichelt², Tomomi Furihata⁹, Christina Guttmann-Gruber², Josefina Piñón Hofbauer¹⁰

Affiliations

¹ EB House Austria, Research Program for the Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Salzburg, Austria; Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
² EB House Austria, Research Program for the Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Salzburg, Austria.
³ Materials Chemistry, Paris Lodron University Salzburg, Salzburg, Austria.
⁴ Department of Cell Biology and Physiology, Paris Lodron University Salzburg, Salzburg, Austria.
⁵ St. John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
⁶ Fundación DEBRA Chile, Santiago, Chile; Centro de Genética y Genómica, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.
⁷ Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
⁸ Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Salzburg, Austria.
⁹ Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan; Department of Pharmacology, Graduate School of Medicine, Chiba University, Chiba, Japan.
¹⁰ EB House Austria, Research Program for the Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Salzburg, Austria. Electronic address: j.d.pinon@salk.at.

PMID: 29203361
DOI: 10.1016/j.jid.2017.11.022

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biomarkers, Tumor
Carcinoma, Squamous Cell / etiology*
Epidermolysis Bullosa Dystrophica / complications*
Extracellular Vesicles*
Humans
Mice
Solute Carrier Organic Anion Transporter Family Member 1B3 / genetics*

Substances

Biomarkers, Tumor
SLCO1B3 protein, human
Solute Carrier Organic Anion Transporter Family Member 1B3