Central mucoepidermoid carcinoma: An up-to-date analysis of 147 cases and review of prognostic factors

Abstract

Objective: To integrate the available data published on central mucoepidermoid carcinoma (CMC) into a comprehensive analysis of its clinical aspects, histology, treatment, and prognostic factors.

Methods: An electronic search was undertaken in July 2017. Eligibility criteria for publications included having clinical, histological, treatment, and time of follow-up data to confirm the diagnosis.

Results: In addition, gender, histological grade, conservative treatment, and lymph node metastasis were significant independent prognostic factors.

Conclusion: Male patients with histological grade III CMC of the jaw bone, who used conservative treatment as the main treatment, and presented with lymph node metastasis, were more likely to have a worse prognosis.

Keywords: Bone lesion; Central mucoepidermoid carcinoma; Jaw bones; Prognostic.