Reverse Translation in Advancing Pharmacotherapy in Pediatric Rheumatology: A Logical Approach in Rare Diseases with Limited Resources

Clin Transl Sci. 2018 Mar;11(2):106-108. doi: 10.1111/cts.12513. Epub 2017 Nov 28.

Authors

Mara L Becker^{1

2}, Ryan S Funk^{1

3}

Affiliations

¹ Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Kansas City, Kansas City, Missouri, USA.
² Division of Rheumatology, Children's Mercy Kansas City, Kansas City, Missouri, USA.
³ Department of Pharmacy Practice, University of Kansas Medical Center, Kansas City, Kansas, USA.

No abstract available

MeSH terms

Antirheumatic Agents / pharmacology
Antirheumatic Agents / therapeutic use*
Arthritis, Juvenile / drug therapy*
Arthritis, Juvenile / immunology
Child
Health Resources
Humans
Interleukin 1 Receptor Antagonist Protein / pharmacology
Interleukin 1 Receptor Antagonist Protein / therapeutic use
Methotrexate / pharmacology
Methotrexate / therapeutic use
Rare Diseases / drug therapy*
Rare Diseases / immunology
Rheumatology / economics
Rheumatology / methods*
Translational Research, Biomedical / economics
Translational Research, Biomedical / methods
Treatment Outcome

Substances

Antirheumatic Agents
Interleukin 1 Receptor Antagonist Protein
Methotrexate