TLR7, a third signal for the robust generation of spontaneous germinal center B cells in systemic lupus erythematosus

Cell Mol Immunol. 2018 Mar;15(3):286-288. doi: 10.1038/cmi.2017.123. Epub 2017 Nov 27.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antibodies, Antinuclear / blood
  • B-Lymphocytes / immunology*
  • Cell Differentiation
  • Clonal Selection, Antigen-Mediated
  • Cyclin D3 / genetics
  • Disease Models, Animal
  • Germinal Center / immunology*
  • Humans
  • Immune Tolerance
  • Lupus Erythematosus, Systemic / immunology*
  • Lymphocyte Activation
  • Mice
  • Mice, Knockout
  • Receptors, Antigen, B-Cell / metabolism
  • Signal Transduction
  • T-Lymphocytes, Helper-Inducer / immunology*
  • Toll-Like Receptor 7 / genetics
  • Toll-Like Receptor 7 / metabolism*

Substances

  • Antibodies, Antinuclear
  • Ccnd3 protein, mouse
  • Cyclin D3
  • Receptors, Antigen, B-Cell
  • Toll-Like Receptor 7