Frontiers in Toxicogenomics in the Twenty-First Century-the Grand Challenge: To Understand How the Genome and Epigenome Interact with the Toxic Environment at the Single-Cell, Whole-Organism, and Multi-Generational Level

Front Genet. 2017 Nov 9:8:173. doi: 10.3389/fgene.2017.00173. eCollection 2017.

Douglas M Ruden^{1

2

3}, Katherine Gurdziel^{1

2

3}, Michael Aschner⁴

¹ Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, United States.
² C. S. Mott Center for Human Health and Development, Wayne State University, Detroit, MI, United States.
³ Institute of Environmental Health Sciences, Wayne State University, Detroit, MI, United States.
⁴ Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, United States.

No abstract available

Keywords: ATAC-seq; RNA-Seq; ScRNA-seq; multigenerational epigenetics; organoids; toxicogenomics; transgenerational epigenetics.

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