Medical abortion reversal: science and politics meet

Am J Obstet Gynecol. 2018 Mar;218(3):315.e1-315.e6. doi: 10.1016/j.ajog.2017.11.555. Epub 2017 Nov 12.

Abstract

Medical abortion is a safe, effective, and acceptable option for patients seeking an early nonsurgical abortion. In 2014, medical abortion accounted for nearly one third (31%) of all abortions performed in the United States. State-level attempts to restrict reproductive and sexual health have recently included bills that require physicians to inform women that a medical abortion is reversible. In this commentary, we will review the history, current evidence-based regimen, and regulation of medical abortion. We will then examine current proposed and existing abortion reversal legislation. The objective of this commentary is to ensure physicians are armed with rigorous evidence to inform patients, communities, and policy makers about the safety of medical abortion. Furthermore, given the current paucity of evidence for medical abortion reversal, physicians and policy makers can dispel bad science and misinformation and advocate against medical abortion reversal legislation.

Keywords: medical abortion; mifepristone; reversal.

Publication types

  • Review

MeSH terms

  • Abortifacient Agents*
  • Abortion, Legal / legislation & jurisprudence*
  • Abortion, Legal / methods
  • Antidotes*
  • Counseling / legislation & jurisprudence
  • Female
  • Humans
  • Patient Education as Topic / legislation & jurisprudence*
  • Politics
  • Pregnancy
  • United States

Substances

  • Abortifacient Agents
  • Antidotes