Treatment and Outcomes of Working Aged Adults with Stroke: Results from a National Prospective Registry

Neuroepidemiology. 2017;49(3-4):113-120. doi: 10.1159/000484141. Epub 2017 Nov 14.

Abstract

Background: Given the potential differences in etiology and impact, the treatment and outcome of younger patients (aged 18-64 years) require examination separately to older adults (aged ≥65 years) who experience acute stroke.

Methods: Data from the Australian Stroke Clinical Registry (2010-2015) including demographic and clinical characteristics, provision of evidence-based therapies and health-related quality of life (HRQoL) post-stroke was used. Descriptive statistics and multilevel regression models were used for group comparisons.

Results: Compared to older patients (age ≥65 years) among 26,220 registrants, 6,526 (25%) younger patients (age 18-64 years) were more often male (63 vs. 51%; p < 0.001), born in Australia (70 vs. 63%; p < 0.001), more often discharged home from acute care (56 vs. 38%; p < 0.001), and less likely to receive antihypertensive medication (61 vs. 73%; p < 0.001). Younger patients had a 74% greater odds of having lower HRQoL compared to an equivalent aged-matched general population (adjusted OR 1.74, 95% CI 1.56-1.93, p < 0.001).

Conclusions: Younger stroke patients exhibited distinct differences from their older counterparts with respect to demographic and clinical characteristics, prescription of antihypertensive medications and residual health status.

Keywords: Registries; Stroke; Stroke registries; Young adult.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Antihypertensive Agents / therapeutic use
  • Australia
  • Female
  • Health Status*
  • Humans
  • Male
  • Middle Aged
  • Patient Discharge / statistics & numerical data*
  • Prospective Studies
  • Quality of Life
  • Registries
  • Stroke / epidemiology*
  • Stroke / therapy*
  • Treatment Outcome
  • Young Adult

Substances

  • Antihypertensive Agents