Objectives: Bacteria belonging to the genera Ochrobactrum and Achromobacter are bacteria considered opportunistic, causing infections mainly in immunocompromised patients. β-lactamases are the main cause of resistance to β-lactam antibiotics. This study aimed to investigate the antimicrobial resistance profile and the presence of β-lactamases encoding genes in Ochrobactrum sp. and Achromobacter sp. isolated from Brazilian soils.
Methods: Soil samples from the five regions of Brazil were collected for the isolation of bacteria, which were identified molecularly and then, the minimum inhibitory concentration and detection of β-lactamases encoding genes were performed.
Results: High-level of resistance to β-lactam antibiotics and different β-lactamases encoding genes were found (blaCTX-M-Gp1, blaSHV, blaOXA-1-like and blaKPC), including the first report of the presence of blaKPC in bacteria belonging to the genera Ochrobactrum and Achromobacter.
Conclusion: The results showed that the bacteria from this study, belonging to genera Ochrobactrum and Achromobacter isolated from soil, harbor different β-lactamases encoding genes and can act as a reservoir of these genes.
Keywords: Achromobacter sp.; Antimicrobial resistance; Ochrobactrum sp.; Soil; β-Lactamase.
Copyright © 2017 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.