Primary mediastinal choriocarcinoma in male is not a very common disease, with nonspecific clinical manifestations. Gynecomastia and testicular atrophy are present in some cases. The levels of serum human chorionic gonadotropin are often significantly increased. Giant lump in the mediastinum and bilateral lungs multiple metastases can be seen on the computed tomography for lung. The diagnosis for it depends on pathological biopsy. Current treatment method is a comprehensive, consisting of chemotherapy, radiotherapy and surgery. This paper reported a case of primary mediastinal choriocarcinoma in male, who were diagnosed and treated in the Second Xiangya Hospital of Central South University. He was admitted for cough and hemoptysis, and finally diagnosed by biopsy. The prognosis is very poor. Therefore, it is important to take physical examination regularly because it can be detected and diagnosed early.
男性原发性纵隔绒癌并不多见，无特异性临床表现，体格检查可发现男性乳腺女性化、睾丸缩小，血清人绒毛膜促性腺激素常显著升高，肺部CT主要表现为纵隔巨大肿块伴双肺多发转移灶，确诊需依靠病理活检，目前的治疗方法包括化学治疗、放射治疗、手术治疗在内的综合治疗。中南大学湘雅二医院收治1例原发于纵隔的男性绒癌患者，以“咳嗽、咯血”就诊，经多次穿刺活检确诊。本病预后差，定期全面体检、早期发现及诊断对于改善疾病的预后有重要的作用。.