[Constant-flow drug administration in anesthesia]

Cah Anesthesiol. 1988 Sep;36(5):365-6.
[Article in French]

Abstract

The authors describe a technique of constant flow perfusion of several anaesthetic drugs, using a simple formula to adjust the perfusion rate to the weight of the patients. Calculation of dilutions is easy: the drug concentration is equal to ten times the rate, per hour and per kg, in practical cases. The flow rate is then a tenth of the patient's weight. This method is easy to apply to several drugs, of which pharmacokinetic parameters justify this administration mode: alfentanil, etomidate, vecuronium bromide... but clinical and instrumental observations should be taken into account for the adjustment of the flow.

Publication types

  • English Abstract

MeSH terms

  • Alfentanil
  • Anesthetics / administration & dosage*
  • Etomidate / administration & dosage
  • Fentanyl / administration & dosage
  • Fentanyl / analogs & derivatives
  • Humans
  • Hypnotics and Sedatives / administration & dosage*
  • Infusions, Intravenous
  • Neuromuscular Blocking Agents / administration & dosage*
  • Vecuronium Bromide / administration & dosage

Substances

  • Anesthetics
  • Hypnotics and Sedatives
  • Neuromuscular Blocking Agents
  • Alfentanil
  • Vecuronium Bromide
  • Fentanyl
  • Etomidate