Asthma exacerbations and socio-economic status in French adults with persistent asthma: A prospective cohort study

J Asthma. 2018 Oct;55(10):1043-1051. doi: 10.1080/02770903.2017.1391280. Epub 2017 Nov 13.

Abstract

Introduction: Adults disadvantaged by poor socio-economic status (SES) are more severely affected by asthma compared to those with better SES. We aimed to determine whether the frequency of asthma exacerbations (AEx), as well as aspects related to AEx management, differed based on SES in patients treated with daily treatments.

Methods: This study, part of the prospective observational cohort ASTRO-LAB, included French adult patients with persistent asthma. Patients were considered as low SES if they benefited from publicly funded special health insurance and/or were perceived as low SES by their general practitioner. AEx was defined as at least one of the following: asthma-related oral corticosteroid course, medical contact, hospitalization, and death. We examined associations between SES and AEx frequency, perceived triggering factors and type of medical contact after AEx.

Results: In our sample of 255 patients, 11.40% were considered as low SES. Patients with low SES did not report significantly more AEx than medium/high SES patients during one-year follow-up (0.79 versus 0.55, p = 0.38). The type of medical contact during AEx differed significantly between the two groups (p = 0.03): patients with medium/high SES consulted their general practitioner more frequently (OR = 2.23, 95% CI = 0.91-5.50, p = 0.08) and were less likely to visit an emergency department or be hospitalized (OR = 0.27, 95% CI = 0.09-0.84, p = 0.02).

Conclusions: AEx frequency did not differ significantly between low and medium/high SES patients, but differences were found in the management of AEx. Studies are needed to better understand the relation between precariousness and management of asthma.

Keywords: Asthma; cohort studies; primary care; social determinants of health; symptom flare-up.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anti-Asthmatic Agents / administration & dosage
  • Anti-Asthmatic Agents / therapeutic use*
  • Asthma / drug therapy*
  • Asthma / epidemiology
  • Asthma / physiopathology*
  • Body Mass Index
  • Comorbidity
  • Emergency Service, Hospital / statistics & numerical data
  • Female
  • France
  • General Practice / statistics & numerical data
  • Humans
  • Hypersensitivity, Immediate / epidemiology
  • Male
  • Medical Assistance / statistics & numerical data
  • Prospective Studies
  • Severity of Illness Index
  • Socioeconomic Factors*
  • Young Adult

Substances

  • Anti-Asthmatic Agents