[Brucellosis in Chile: Description of a series of 13 cases]

Rev Chilena Infectol. 2017 Jun;34(3):243-247. doi: 10.4067/S0716-10182017000300006.
[Article in Spanish]

Abstract

Introduction: Brucellosis is a zoonosis caused by Brucella spp. It may be acquired by consuming unpasteurized dairy products. Brucellosis has a low incidence in Chile, thus, we have a scarce data.

Aim: To report and to characterize the first series of clinical cases of adult patients diagnosed with brucellosis in Chile.

Methods: We describe a series of 13 clinical cases in patients diagnosed between 2000 and 2016 in three different centers in the Metropolitan Region, Chile. A retrospective analysis was performed on clinical presentation, laboratory, antibiotic treatment, morbidity and mortality.

Results: The mean age was 50 years old. Eight cases had a record of consumption of unpasteurized dairy products. The most frequently reported complaints were fever. The most frequent focal point involved was the spine. Only one patient had a positive blood culture, while the diagnosis was made using serological techniques in the other part of the group. The most indicated antibiotic regimens were doxycycline-rifampicin and doxycycline-gentamicin. The hospital stay was 20 days approximately as an average. Clinical cure was achieved in all cases.

Conclusions: Brucellosis is an infrequent zoonosis in Chile, and it produces a nonspecific clinical picture, so it is necessary to have high suspicion to make the diagnosis based in the antecedent of consumption of unpasteurized dairy or raw meat.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Brucellosis / diagnosis*
  • Brucellosis / drug therapy
  • Brucellosis / epidemiology
  • Brucellosis / etiology
  • Chile / epidemiology
  • Dairy Products / microbiology
  • Doxycycline / administration & dosage
  • Drug Therapy, Combination
  • Female
  • Gentamicins / administration & dosage
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Retrospective Studies
  • Rifampin / administration & dosage
  • Urban Population
  • Young Adult

Substances

  • Gentamicins
  • Doxycycline
  • Rifampin