Follicular Dendritic Cell Sarcoma of the Larynx: Apropos a Rare Case with Review of the Literature

Turk Patoloji Derg. 2019;35(3):254-257. doi: 10.5146/tjpath.2017.01408.

Abstract

Extranodal follicular dendritic cell sarcomas are extremely rare neoplasms included under the hematolymphoid and dendritic group of neoplasms. Histologically, fascicular, whorled spindle cells with sprinkled lymphocytes are typical; however higher grade epithelioid morphology seen in a subset makes diagnosis of follicular dendritic cell sarcoma challenging. Rarity of occurrence, a wide histologic spectrum and a long list of differential diagnostic entities render follicular dendritic cell sarcoma an under-recognized entity susceptible to diagnostic pitfalls. Application of a judicious panel of immunohistochemical markers is imperative to avoid errors in diagnosis and patient management. We report here an extremely rare case of follicular dendritic cell sarcoma of the larynx- a hitherto unreported site.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Dendritic Cell Sarcoma, Follicular / diagnosis*
  • Dendritic Cell Sarcoma, Follicular / pathology*
  • Humans
  • Laryngeal Neoplasms / diagnosis*
  • Laryngeal Neoplasms / pathology*
  • Male
  • Middle Aged