Challenges in the Design and Interpretation of Noninferiority Trials

N Engl J Med. 2017 Oct 5;377(14):1357-1367. doi: 10.1056/NEJMra1510063.

Authors

Laura Mauri¹, Ralph B D'Agostino Sr¹

Affiliation

¹ From the Division of Cardiovascular Medicine, Brigham and Women's Hospital (L.M.), Harvard Medical School (L.M.), the Department of Mathematics and Statistics, Boston University (R.B.D.), and Baim Institute for Clinical Research (L.M., R.B.D.) - all in Boston.

PMID: 28976859
DOI: 10.1056/NEJMra1510063

No abstract available

Publication types

Review

MeSH terms

Data Interpretation, Statistical
Humans
Randomized Controlled Trials as Topic / methods*
Randomized Controlled Trials as Topic / standards
Research Design*