Personalized Medicine and Infectious Disease Management

Slade O Jensen; Sebastiaan J van Hal

doi:10.1016/j.tim.2017.09.006

Personalized Medicine and Infectious Disease Management

Trends Microbiol. 2017 Nov;25(11):875-876. doi: 10.1016/j.tim.2017.09.006. Epub 2017 Sep 29.

Authors

Slade O Jensen¹, Sebastiaan J van Hal²

Affiliations

¹ School of Medicine, Western Sydney University, Sydney, NSW, Australia; Antimicrobial Resistance and Mobile Elements Group, Ingham Institute for Applied Medical Research, Sydney, NSW, Australia. Electronic address: s.jensen@westernsydney.edu.au.
² Royal Prince Alfred Hospital, Sydney, NSW, Australia.

PMID: 28969882
DOI: 10.1016/j.tim.2017.09.006

Abstract

A recent study identified pathogen factors associated with an increased mortality risk in Staphylococcus aureus bacteremia, using predictive modelling and a combination of genotypic, phenotypic, and clinical data. This study conceptually validates the benefit of personalized medicine and highlights the potential use of whole genome sequencing in infectious disease management.

Keywords: infectious disease management; personalized medicine; whole-genome sequencing.

Publication types

Comment

MeSH terms

Bacteremia / genetics*
Bacteremia / therapy*
DNA, Bacterial / blood
DNA, Bacterial / genetics
Disease Management
Genomics
Host-Pathogen Interactions
Humans
Mutation
Precision Medicine / methods*
Staphylococcal Infections / genetics*
Staphylococcal Infections / therapy*
Staphylococcus aureus / pathogenicity*
Time Factors
Whole Genome Sequencing

Substances

DNA, Bacterial