Intrahepatic Cholangiolocellular and Cholangiocellular Carcinoma - Differences in the 18F-FDG PET/CT Findings

Intern Med. 2017 Nov 15;56(22):3027-3031. doi: 10.2169/internalmedicine.8839-17. Epub 2017 Sep 25.

Abstract

Cholangiolocellular carcinoma is a minor primary cancerous tumor of the liver and its coexistence with intrahepatic cholangiocarcinoma in the liver is rare. We herein report a case of concurrent cholangiolocellular carcinoma and intrahepatic cholangiocarcinoma in the liver, in addition to a rectal G1 neuroendocrine tumor, a so-called carcinoid. The intrahepatic tumors showed a different uptake in the 18F-fluoro-2-deoxyglucose (FDG) positron-emission tomography (PET)/computed tomography (CT) findings. In addition to conventional dynamic contrast-enhanced CT, we concluded that FDG PET/CT could therefore be a helpful modality to identify the properties of both cholangiolocellular carcinoma and intrahepatic cholangiocarcinoma.

Keywords: 18F-fluoro-2-deoxyglucose positron emission tomography/computed tomography; cholangiocellular carcinoma; cholangiolocellular carcinoma; combined hepatocellular cholangiocarcinoma; neuroendocrine tumor; with stem cell features.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Bile Duct Neoplasms / pathology
  • Bile Ducts, Intrahepatic / pathology
  • Cholangiocarcinoma / diagnostic imaging
  • Cholangiocarcinoma / pathology*
  • Fluorodeoxyglucose F18
  • Humans
  • Liver Neoplasms / pathology*
  • Male
  • Positron Emission Tomography Computed Tomography
  • Rectal Neoplasms / diagnostic imaging
  • Rectal Neoplasms / pathology
  • Tomography, Spiral Computed

Substances

  • Fluorodeoxyglucose F18