Favorable results from a prospective evaluation of 200 patients with large hiatal hernias undergoing LINX magnetic sphincter augmentation

Surg Endosc. 2018 Apr;32(4):1762-1768. doi: 10.1007/s00464-017-5859-4. Epub 2017 Sep 21.

Abstract

Introduction: Magnetic sphincter augmentation (MSA) of the lower esophageal sphincter restores the antireflux barrier in patients with hiatal hernias ≤3 cm. We performed a prospective study in patients undergoing MSA with the LINX device during repair of paraesophageal and hernias over 3 cm axial component.

Methods and procedures: Multicenter, prospective study of consecutive patients treated with MSA at the time of repair of hiatal hernias >3 cm.

Results: 200 patients (110 female) were treated between March 2014 and February 2017 via laparoscopic hernia repair and MSA. Mean age was 59.5 years, mean BMI 29.4. 40% had esophagitis, 20% intestinal metaplasia, 72 of 77 tested had abnormal pH studies. Preoperative PPI use was reported by 87%. Eighteen patients had prior hiatal hernia/fundoplication. All had normal function. 78% of patients had axial hiatal hernia ≥5 cm or large paraesophageal component. Mean operative time was 81 min (38-193), EBL was 10 cc. Non-permanent mesh reinforcement of hiatal repair was performed in 83% of the patients. There were two readmissions for dehydration; 2 patients with pulmonary embolism, and 1 patient with cardiac ischemia. Nineteen patients required dilation. 156 pts were followed at a median of 8.6 months. GERD-HRQL scores improved from 26 preoperatively to 2 postoperatively. Complete PPI independence was achieved in 94% (147/156). Videoesophagram in 51 patients at median 11 months found 3 asymptomatic hernias <3 cm. One symptomatic patient underwent successful repair of the hernia without MSA manipulation. There have been no device explants, erosions, or migrations to date.

Conclusions: This prospective study of 200 patients with >3 cm hernias undergoing MSA with hiatoplasty resulted in favorable outcomes with median of 9 months follow-up. Comparing this to published reports of MSA in patients with <3 cm hernias, the safety and clinical efficacy of MSA are independent of initial hernia size.

Keywords: GERD; Hiatal hernia; LINX; MSA; Magnetic sphincter augmentation; Paraesophageal hernia.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Esophageal Sphincter, Lower / surgery*
  • Female
  • Fundoplication*
  • Gastroesophageal Reflux / surgery
  • Hernia, Hiatal / surgery*
  • Herniorrhaphy / legislation & jurisprudence*
  • Humans
  • Laparoscopy* / methods
  • Male
  • Middle Aged
  • Prospective Studies
  • Treatment Outcome