[Randomized controlled study: Sophora flavescens gel in treatment of cervical HPV infection]

Zhongguo Zhong Yao Za Zhi. 2016 Nov;41(21):4072-4075. doi: 10.4268/cjcmm20162129.
[Article in Chinese]

Abstract

This study aimed to evaluate the efficacy of Sophora flavescens gel in treatment of cervical HPV infection. 120 patients with cervical HPV infections were selected from department of gynecology, the first affiliated hospital, Heilongjiang university of Chinese medicine. They were randomly divided into three groups: test group(S. flavescens gel, 40 cases), control group(human recombinant interferon α-2b gel, 40 cases) and combined application group(combination of the above two, 40 cases). The treatment course was three months in all three groups. Before and after treatment, the changes of HPV viral load and the changes of viral load for different HPV types were observed.The results could provide guidance for clinical application of S. flavescens gel.

Keywords: HPV infection; HPV type; Sophora flavescens gel; human recombinant interferon α-2b gel; viral load.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Cervix Uteri / virology
  • DNA, Viral
  • Drugs, Chinese Herbal / therapeutic use*
  • Female
  • Gels
  • Humans
  • Papillomavirus Infections / drug therapy*
  • Sophora / chemistry*
  • Viral Load

Substances

  • DNA, Viral
  • Drugs, Chinese Herbal
  • Gels