CD4 T cell-restricted IL-2 signaling defect in a patient with a novel IFNGR1 deficiency

J Allergy Clin Immunol. 2018 Jan;141(1):435-439.e7. doi: 10.1016/j.jaci.2017.08.018. Epub 2017 Sep 18.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers
  • CD4-Positive T-Lymphocytes / immunology*
  • CD4-Positive T-Lymphocytes / metabolism*
  • Female
  • Genetic Association Studies*
  • Genetic Predisposition to Disease*
  • Humans
  • Immunophenotyping
  • Infant
  • Interferon gamma Receptor
  • Interleukin-2 / metabolism*
  • Lymphocyte Count
  • Lymphocyte Subsets / immunology
  • Lymphocyte Subsets / metabolism
  • Phenotype
  • Receptors, Interferon / deficiency*
  • Sequence Analysis, DNA
  • Signal Transduction*

Substances

  • Biomarkers
  • Interleukin-2
  • Receptors, Interferon