Ongoing large measles outbreak with nosocomial transmission in Milan, northern Italy, March-August 2017

Euro Surveill. 2017 Aug 17;22(33):30596. doi: 10.2807/1560-7917.ES.2017.22.33.30596.

Abstract

A large measles outbreak has been ongoing in Milan and surrounding areas. From 1 March to 30 June 2017, 203 measles cases were laboratory-confirmed (108 sporadic cases and 95 related to 47 clusters). Phylogenetic analysis revealed the co-circulation of two different genotypes, D8 and B3. Both genotypes caused nosocomial clusters in two hospitals. The rapid analysis of epidemiological and phylogenetic data allowed effective surveillance and tracking of transmission pathways.

Keywords: Epidemiology; Measles; Nosocomial transmission; Outbreaks; Phylogeny; Surveillance.

MeSH terms

  • Cross Infection / epidemiology*
  • Disease Outbreaks*
  • Female
  • Genotype
  • Humans
  • Infectious Disease Transmission, Patient-to-Professional*
  • Italy / epidemiology
  • Measles / epidemiology
  • Measles / transmission*
  • Measles / virology
  • Measles virus / genetics*
  • Measles virus / isolation & purification
  • Molecular Epidemiology
  • Occupational Exposure*
  • Population Surveillance
  • RNA, Viral / genetics
  • Risk Factors
  • Sequence Analysis, DNA

Substances

  • RNA, Viral