Mycoplasma genitalium From Basic Science to Public Health: Summary of the Results From a National Institute of Allergy and Infectious Disesases Technical Consultation and Consensus Recommendations for Future Research Priorities

J Infect Dis. 2017 Jul 15;216(suppl_2):S427-S430. doi: 10.1093/infdis/jix147.

Abstract

This article lays out the research priorities for Mycoplasma genitalium research agreed upon by the participants in a 2016 National Institutes of Allergy and Infectious Diseases-funded Technical Consultation focused on this organism. The state of current knowledge concerning the microbiology, epidemiology, clinical manifestations of infection, treatment, and public health significance of M. genitalium reviewed at the meeting is described in detail in the individual articles included in this supplemental edition of the Journal of Infectious Diseases. Here we summarize the points made in these articles most relevant to the formulation of the research priorities listed in this article. The most important recommendation resulting from this Technical Consultation is the initiation of clinical trials designed to determine definitively whether screening for and treatment of M. genitalium infections in women and their sexual partners improve reproductive health in women and/or prevent human immunodeficiency virus transmission.

Keywords: HIV infection; Mycoplasma genitalium; antibiotic resistance; clinical trials; diagnosis.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Clinical Trials as Topic
  • Consensus
  • Drug Resistance, Microbial
  • Female
  • HIV Infections / prevention & control
  • HIV Infections / transmission
  • Humans
  • Mycoplasma Infections / diagnosis*
  • Mycoplasma Infections / drug therapy
  • Mycoplasma Infections / epidemiology*
  • Mycoplasma genitalium*
  • National Institutes of Health (U.S.)
  • Practice Guidelines as Topic
  • Public Health / trends*
  • Research / trends*
  • United States

Substances

  • Anti-Bacterial Agents