The C-terminal multimerization domain is essential for leukemia development by CBFβ-SMMHC in a mouse knockin model

Leukemia. 2017 Dec;31(12):2841-2844. doi: 10.1038/leu.2017.262. Epub 2017 Aug 18.
No abstract available

Publication types

  • Research Support, N.I.H., Intramural

MeSH terms

  • Animals
  • Carcinogenesis / genetics
  • Core Binding Factor alpha Subunits / genetics
  • Epigenetic Repression
  • Heterozygote
  • Leukemia / genetics*
  • Mice
  • Mice, Transgenic
  • Mutation
  • Myosin Heavy Chains / genetics*
  • Oncogene Proteins, Fusion / genetics*
  • Protein Domains / genetics
  • Transcription, Genetic

Substances

  • CBFbeta-MYH11 fusion protein
  • Core Binding Factor alpha Subunits
  • Oncogene Proteins, Fusion
  • Myosin Heavy Chains