The role of luminal Ca regulation in Ca signaling refractoriness and cardiac arrhythmogenesis

J Gen Physiol. 2017 Sep 4;149(9):877-888. doi: 10.1085/jgp.201711808. Epub 2017 Aug 10.

Abstract

Györke et al. discuss the role of sarcoplasmic reticulum Ca2+ in cardiac refractoriness and pathological implications.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Arrhythmias, Cardiac / metabolism*
  • Arrhythmias, Cardiac / physiopathology
  • Calcium Signaling*
  • Excitation Contraction Coupling
  • Humans
  • Myocytes, Cardiac / metabolism
  • Myocytes, Cardiac / physiology
  • Sarcoplasmic Reticulum / metabolism