Acalculous Cholecystitis in a Pediatric Patient With Plasmodium Falciparum Infection: A Case Report and Literature Review

Pediatr Infect Dis J. 2018 Feb;37(2):e43-e45. doi: 10.1097/INF.0000000000001734.

Abstract

Malaria has been associated with acute acalculous cholecystitis, a very uncommon complication in children. We present a 5-year-old girl, originally from Equatorial-Guinea, diagnosed with severe malaria with acute kidney injury, thrombocytopenia and acute acalculous cholecystitis. She was treated with intravenous quinine and clindamycin, plus cefotaxime and metronidazole with a full resolution without surgery.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acalculous Cholecystitis / complications*
  • Acalculous Cholecystitis / drug therapy
  • Acute Kidney Injury / complications
  • Administration, Intravenous
  • Anti-Bacterial Agents / therapeutic use
  • Antimalarials / therapeutic use
  • Cefotaxime / therapeutic use
  • Child, Preschool
  • Clindamycin / therapeutic use
  • Female
  • Humans
  • Malaria, Falciparum / complications*
  • Malaria, Falciparum / drug therapy
  • Metronidazole / therapeutic use
  • Plasmodium falciparum*
  • Quinine / therapeutic use
  • Thrombocytopenia / complications

Substances

  • Anti-Bacterial Agents
  • Antimalarials
  • Metronidazole
  • Clindamycin
  • Quinine
  • Cefotaxime