Anti-epileptic drugs induce cutaneous lymphocyte-associated antigen downregulation leading to potential human herpes virus-7 reactivation in clinically asymptomatic patients

J Eur Acad Dermatol Venereol. 2018 Feb;32(2):e41-e43. doi: 10.1111/jdv.14493. Epub 2017 Oct 10.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Anticonvulsants / adverse effects
  • Anticonvulsants / pharmacology*
  • CD4 Lymphocyte Count
  • CD4-Positive T-Lymphocytes / metabolism*
  • Cells, Cultured
  • Down-Regulation / drug effects
  • Drug Eruptions / etiology
  • Female
  • Herpesvirus 7, Human / physiology*
  • Humans
  • Leukocytes, Mononuclear
  • Lewis X Antigen / analogs & derivatives
  • Lewis X Antigen / metabolism
  • Male
  • Middle Aged
  • Oligosaccharides / metabolism*
  • Sialyl Lewis X Antigen / analogs & derivatives
  • T-Lymphocytes, Regulatory
  • Valproic Acid / pharmacology
  • Virus Activation / drug effects*

Substances

  • 6-sulfo sialyl Lewis X
  • Anticonvulsants
  • Lewis X Antigen
  • Oligosaccharides
  • Sialyl Lewis X Antigen
  • Valproic Acid