Assay Interference by Aggregation
Review
In: Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004.
2017 Jul 26
.
Authors
Douglas S. Auld
1
,
James Inglese
2
3
,
Jayme L. Dahlin
4
Book Editors
Sarine Markossian
1
,
Abigail Grossman
1
,
Michelle Arkin
2
,
Douglas Auld
3
,
Chris Austin
4
,
Jonathan Baell
5
,
Kyle Brimacombe
1
,
Thomas D.Y. Chung
6
,
Nathan P. Coussens
7
,
Jayme L. Dahlin
8
,
Viswanath Devanarayan
9
,
Timothy L. Foley
10
,
Marcie Glicksman
11
,
Kirill Gorshkov
12
,
Joseph V. Haas
13
,
Matthew D. Hall
1
,
Samuel Hoare
14
,
James Inglese
1
,
Philip W. Iversen
15
,
Madhu Lal-Nag
16
,
Zhuyin Li
12
,
Jason R. Manro
13
,
James McGee
13
,
Owen McManus
17
,
Mackenzie Pearson
13
,
Terry Riss
18
,
Peter Saradjian
19
,
G. Sitta Sittampalam
1
,
Mike Tarselli
20
,
O. Joseph Trask Jr.
21
,
Jeffrey R. Weidner
22
,
Mary Jo Wildey
23
,
Kelli Wilson
1
,
Menghang Xia
1
,
Xin Xu
1
Affiliations
1
Novartis Institutes for Biomedical Research, Cambridge, MA, USA
2
National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA
3
National Human Genome Research Institute, Bethesda, MD, USA
4
Department of Pathology, Brigham and Women’s Hospital, Boston, MA, USA
Book Affiliations
1
National Center for Advancing Translational Sciences, National Institutes of Health
2
University of California, San Francisco
3
Novartis Institutes for Biomedical Research
4
GSK plc
5
Lyterian Therapeutics
6
Sanford Burnham Prebys Medical Discovery Institute
7
Frederick National Laboratory for Cancer Research
8
Agios Pharmaceuticals
9
Eisai, Inc
10
Pfizer Inc
11
EnClear Therapies
12
Bristol Myers Squibb
13
Eli Lilly and Company
14
Pharmechanics, LLC
15
Luther College
16
InSphero AG
17
Quiver Bioscience
18
Promega Corporation
19
Beth Israel Deaconess Medical Center
20
TetraScience
21
Revvity, Inc.
22
QualSci Consulting, LLC
23
Merck & Co., Inc.
PMID:
28749639
Bookshelf ID:
NBK442297
No abstract available
Sections
Abstract
Flowchart
Abbreviations
Introduction and Background
Strategies to Mitigate Incidence of Aggregation in Biochemical Assays
Strategies to Identify Aggregation
Frequently Asked Questions
Conclusions
Suggested Web Resources
Suggested Readings (alphabetical order)
Acknowledgements
REFERENCES
Publication types
Review